ROSUVASTATIN (roe SOO va sta tin) treats high cholesterol and reduces the risk of heart attack and stroke. It works by decreasing bad cholesterol and fats (such as LDL, triglycerides) and increasing good cholesterol (HDL) in your blood. It belongs to a group of medications called statins. Changes to diet and exercise are often combined with this medication.
What should I tell my care team before I take this medication?
They need to know if you have any of these conditions:
Diabetes
Frequently drink alcohol
Kidney disease
Liver disease
Muscle pain or cramps
Thyroid disease
An unusual or allergic reaction to rosuvastatin, other medications, foods, dyes, or preservatives
Pregnant or trying to get pregnant
Breastfeeding
How should I use this medication?
Take this medication by mouth with water. Take it as directed on the prescription label at the same time every day. Do not cut, crush, or chew this medication. Swallow the capsules whole. You may open the capsule and put the contents on at least 1 teaspoon of room temperature applesauce or chocolate/vanilla flavored pudding. Stir the mixture for 10 to 15 seconds. Swallow the entire mixture right away. Do not chew it. You can take it with or without food. If it upsets your stomach, take it with food. Keep taking it unless your care team tells you to stop.
Take antacids with aluminum and magnesium hydroxide in them at a different time of day than this medication. Take antacids 2 hours after this medication.
Talk to your care team about the use of this medication in children. While it may be prescribed for children as young as 7 years for selected conditions, precautions do apply.
What if I miss a dose?
If you miss a dose, skip it. Take your next dose at the normal time. Do not take extra or 2 doses at the same time to make up for the missed dose.
What may interact with this medication?
Do not take this medication with any of the following:
Red yeast rice
This medication may also interact with the following:
Alcohol
Antacids containing aluminum and magnesium hydroxide
Colchicine
Cyclosporine
Febuxostat
Fostamatinib
Some medications for cancer, such as capmatinib, darolutamide, enasidenib, regorafenib
Some medications for HIV or hepatitis
Other medications for cholesterol
Tafamidis
Teriflunomide
Warfarin
This medication may affect how other medications work, and other medications may affect the way this medication works. Talk with your care team about all the medications you take. They may suggest changes to your treatment plan to lower the risk of side effects and to make sure your medications work as intended.
What side effects may I notice from receiving this medication?
Side effects that you should report to your care team as soon as possible:
Allergic reactions—skin rash, itching, hives, swelling of the face, lips, tongue, or throat
High blood sugar (hyperglycemia)—increased thirst or amount of urine, unusual weakness, fatigue, blurry vision
Liver injury—right upper belly pain, loss of appetite, nausea, light-colored stool, dark yellow or brown urine, yellowing skin or eyes, unusual weakness, fatigue
Muscle injury—unusual weakness, fatigue, muscle pain, dark yellow or brown urine, decrease in amount of urine
Redness, blistering, peeling or loosening of the skin, including inside the mouth
Side effects that usually do not require medical attention (report to your care team if they continue or are bothersome):
Fatigue
Headache
Nausea
Stomach pain
What should I watch for while using this medication?
Visit your care team for regular checks on your progress.
You may need blood work done while you are taking this medication.
Taking this medication is only part of a total heart healthy program. Ask your care team if there are other changes you can make to improve your overall health.
Your care team may tell you to stop taking this medication if you develop muscle problems. If your muscle problems do not go away after stopping this medication, contact your care team.
If you are going to need surgery or a procedure, tell your care team that you are taking this medication.
This medication may increase blood sugar. The risk may be higher in patients who already have diabetes. Ask your care team what you can do to lower your risk of diabetes while taking this medication.
Talk to your care team if you may be pregnant. Serious birth defects can occur if you take this medication during pregnancy. There are benefits and risks to taking medications during pregnancy. Your care team can help you find the option that works for you.
Talk to your care team before breastfeeding. Changes to your treatment plan may be needed.
Where should I keep my medication?
Keep out of the reach of children and pets.
Store at room temperature between 20 and 25 degrees C (68 and 77 degrees F). Protect from moisture. Keep the container tightly closed. Get rid of any unused medication after the expiration date.
To get rid of medications that are no longer needed or expired:
Take the medication to a take-back program. Check with your pharmacy or law enforcement to find a location.
If you cannot return the medication, check the label or package insert to see if the medication should be thrown out in the garbage or flushed down the toilet. If you are not sure, ask your care team. If it is safe to put it in the trash, empty the medication out of the container. Mix it with cat litter, dirt, coffee grounds, or another unwanted substance. Seal the mixture in a bag or container. Put it in the trash.
K Health articles are all written and reviewed by MDs, PhDs, NPs, or PharmDs and are for informational purposes only. This information does not constitute and should not be relied on for professional medical advice. Always talk to your doctor about the risks and benefits of any treatment.
This information is educational only and should not be construed as specific instructions for individual patients nor as a substitute for medical advice, diagnosis or treatment. Talk to your health care provider or pharmacist about the information and instructions. K Health assumes no liability for any use or reliance on this information.
